Summary. Heart palpitations is found among people who take Zyrtec, especially for people who are female, 60+ old , have been taking the drug for 1 month, also take medication Aspirin, and have Hypersensitivity. I am glad all the cardiac test turned out fine but sometimes medicines can give people palpitations, even those with no cardiac problems. I have a friend who takes Zyrtec and it makes her heart race and she has a normal healthy heart. But first, don't take any chances with your heart. See a dr. See a dr. Doctors give unbiased, trusted information on whether Claritin can cause or treat Heart Palpitations: Dr. Stern on claritin heart palpitations: Heart palpitations could be caused by a physical or mental condition. Palpitations (feelings or sensations that your heart is pounding or racing) has been reported by people with high blood pressure, depression, multiple sclerosis, osteoporosis, rheumatoid arthritis (latest reports from 95,286 Palpitations patients). Hi. I was wondering if anyone else experiences problems with their heart and extra beats/palpitations when taking cetirizine or other allergy meds. View detailed reports from patients taking zyrtec who experienced palpitations. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Palpitations are described as an unpleasant awareness of the heart beating or a fast heart rate, called tachycardia. Palpitations and tachycardia can occur with both normal and abnormal heart rhythms and have been reported in conjunction with the use of Zyrtec. Zyrtec Allergies to dust mites, dust mites, sinus infection, heart palpitations, claritin I have allergies to dust mites, and started taking Zyrtec to help get over a sinus infection. It worked great at first. Then I started to feel not myself, and my thoughts were out of control. I have depression, and it magnified it. Can Cetirizine cause Palpitations? Palpitations is a known side effect of Cetirizine. Complete analysis from patient reviews and trusted online health resources, including first-hand experiences. Summary. The most commonly reported Zyrtec side effects include mild drowsiness, headache, sore throat and dry mouth. More serious side effects are heart palpitations, insomnia, tremors, confusion and decreases in urine production.